UAB research makes headway against age-related memory loss

BIRMINGHAM, AL (WBRC) – UAB researchers are claiming to be closer to understanding memory loss in the elderly through the development of a memory boosting drug.

In a May 7th editorial published in the journal "Science," Dr. J. David Sweatt says that drugs called histone deacetylase inhibitors are showing promise of stopping memory loss and boosting memory in animals.

The article was published in conjunction with findings from research from the European Neuroscience Institute at University Goettingen in Germany that supports the UAB findings.

"It's a real proof of concept," said Sweatt. "We've been studying histone deacetylase inhibitors for some 10 years. Studies in our lab and elsewhere strongly suggested that these drugs could potentially reverse aging-associated memory dysfunction.

Sweatt adds that there is still further research to do. So far, the findings have only been found in mouse models.